Russell S. Witte, PhD

Professor, Medical Imaging, Optical Sciences, Biomedical Engineering
Professor, Applied Mathematics - GIDP
Professor, Neurosurgery
Professor, Neuroscience - GIDP

Russell Witte received a BS degree with honors in physics from the University of Arizona in Tucson (1993), and a PhD degree in bioengineering from Arizona State University in 2002. Following travel abroad in Europe and Brazil, he began graduate school at Arizona State University in bioengineering. His doctoral thesis exploited chronic microelectrode arrays to describe sensory coding and cortical plasticity in the mammalian brain. He then moved to the University of Michigan in Ann Arbor and joined the Biomedical Ultrasonics Laboratory to develop new contrast mechanisms for imaging especially the brain, nervous, and muscle tissue.Dr. Witte is currently Associate Professor of Medical Imaging, Optical Sciences and Biomedical Engineering at the University of Arizona. To overcome limitations with traditional ultrasound imaging, which typically exhibits poor contrast in soft tissue, his experimental ultrasound laboratory devises and tests novel contrast mechanisms that integrate ultrasound with light, microwaves or electricity.  We work closely with collaborators in the Colleges of Engineering, Optical Sciences and Medicine, as well as industry, to develop cutting-edge imaging technologies that potentially improve patient care. Dr. Witte is also a member of the Arizona Cancer Center, Sarver Heart Center and School of Mind, Brain, and Behavior, as well as the Neuroscience, Applied Mathematics, and Biomedical Engineering graduate interdisciplinary programs (GIDPs).

Research Interests: 

Ultrasound, Thermoacoustics, Biolectricity, Photoacoustics, Elasticity, Microwaves, Functional Brain Imaging, Behavior, Cardiac Imaging, Cancer Imaging, Smart Contrast Agents, Nanotechnology My team develops new imaging methods using a combination of light, ultrasound and microwaves that potentially affect a variety of medical disorders from arrhythmia and epilepsy to cancer and tendinopathy.

  • MS: Arizona State University, 2000
  • PhD: Arizona State University, 2002

Select Publications


Seckeler, M. D., L. Moedano, D. Mustacich, B. T. Kalb, M. Saranathan, J-P. Galons, and M. H. Witte, "Non-contrast MR lymphography of rare lymphatic abnormalities.", Lymphology, vol. 53, issue 3, pp. 136-140, 2020. PMID: 33350287
Preston, C., A. M. Alvarez, A. Barragan, J. Becker, W. S. Kasoff, and R. S. Witte, "High resolution transcranial acoustoelectric imaging of current densities from a directional deep brain stimulator.", J Neural Eng, vol. 17, issue 1, pp. 016074, 2020 02 27. PMCID: PMC7446234  PMID: 31978914


Preston, P., W. Kasoff, and R. Witte, Selective Mapping of Deep Brain Stimulation Lead Currents Using Acoustoelectric Imaging, 2018.


Taljanovic, M. S., L. H. Gimber, G. W. Becker, D. L Latt, A. S. Klauser, D. M. Melville, L. Gao, and R. S. Witte, "Shear-Wave Elastography: Basic Physics and Musculoskeletal Applications.", Radiographics, vol. 37, issue 3, pp. 855-870, 2017 May-Jun. PMCID: PMC5452887 
Kunyansky, L., C. P. Ingram, and R. S. Witte, "Rotational magneto-acousto-electric tomography (MAET): theory and experimental validation.", Phys Med Biol, vol. 62, issue 8, pp. 3025-3050, 2017 04 21. PMCID: PMC5526336  PMID: 28323633
Fundella, KJ., RS. Witte, and P. Jonathan, Tracking delivery of a drug surrogate in the porcine heart using photoacoustic imaging and spectroscopy, 2017.
Furdella, K. J., R. S. Witte, and J. P. Vande Geest, "Tracking delivery of a drug surrogate in the porcine heart using photoacoustic imaging and spectroscopy.", J Biomed Opt, vol. 22, issue 4, pp. 41016, 2017 04 01.


Gimber, LH., DM. Melville, AS. Klauser, RS. Witte, H. Arif-Tiwari, and MS. Taljanovic, "Artifacts in Musculoskeletal Ultrasound", Radiographics, vol. 36, issue 2, pp. 479-480, 04/2016.
Gimber, L. H., D. M. Melville, A. S. Klauser, R. S. Witte, H. Arif-Tiwari, and M. S. Taljanovic, "Artifacts at Musculoskeletal US: Resident and Fellow Education Feature.", Radiographics, vol. 36, issue 2, pp. 479-80, 2016 Mar-Apr. PMID: 26963457


Qin, Y., Q. Li, P. Ingram, C. Barber, Z. Liu, and R. S. Witte, "Ultrasound current source density imaging of the cardiac activation wave using a clinical cardiac catheter.", IEEE Trans Biomed Eng, vol. 62, issue 1, pp. 241-7, 2015 Jan. PMCID: PMC4406765  PMID: 25122512
Goyal, U., Y. Kim, H. Arif Tiwari, R. Witte, and B. Stea, "A pilot study of ultrasound-guided electronic brachytherapy for skin cancer.", J Contemp Brachytherapy, vol. 7, issue 5, pp. 374-80, 2015 Oct. PMCID: PMC4663218 
Gao, L., J. S. Yuan, G. J. Heden, J. A. Szivek, M. S. Taljanovic, D. L Latt, and R. S. Witte, "Ultrasound elasticity imaging for determining the mechanical properties of human posterior tibial tendon: a cadaveric study.", IEEE Trans Biomed Eng, vol. 62, issue 4, pp. 1179-84, 2015 Apr. PMID: 25532163


Taljanovic, M. S., D. M. Melville, L. R. Scalcione, L. H. Gimber, E. J. Lorenz, and R. S. Witte, "Artifacts in musculoskeletal ultrasonography.", Semin Musculoskelet Radiol, vol. 18, issue 1, pp. 3-11, 2014 Feb.


Peyman, G. A., C. P. Ingram, L. G. Montilla, and R. S. Witte, "A high-resolution 3D ultrasonic system for rapid evaluation of the anterior and posterior segment.", Ophthalmic Surg Lasers Imaging, vol. 43, issue 2, pp. 143-51, 2012 Mar-Apr.


Roach, M., J-L. Alberini, A. Paul Pecking, A. Testori, F. Verrecchia, J. Soteldo, U. Ganswindt, J. L. Joyal, J. W. Babich, R. S. Witte, et al., "Diagnostic and therapeutic imaging for cancer: therapeutic considerations and future directions.", J Surg Oncol, vol. 103, issue 6, pp. 587-601, 2011 May 1.
Bauer, D. R., R. Olafsson, L. G. Montilla, and R. S. Witte, "3-D photoacoustic and pulse echo imaging of prostate tumor progression in the mouse window chamber.", J Biomed Opt, vol. 16, issue 2, pp. 026012, 2011 Feb. PMCID: PMC3065344 


Olafsson, R., D. R. Bauer, L. G. Montilla, and R. S. Witte, "Real-time, contrast enhanced photoacoustic imaging of cancer in a mouse window chamber.", Opt Express, vol. 18, issue 18, pp. 18625-32, 2010 Aug 30.


Witte, R. S., P. J. Rousche, and D. R. Kipke, "Fast wave propagation in auditory cortex of an awake cat using a chronic microelectrode array.", J Neural Eng, vol. 4, issue 2, pp. 68-78, 2007 Jun. PMID: 17409481