Maria I. Altbach, PhD

MI Executive Committee Member
Vice Chair of Research
Professor, Medical Imaging
Professor, Biomedical Engineering

Dr. Altbach's research group is focused on the development of novel magnetic resonance imaging (MRI) techniques for improving the diagnosis of disease. Our group develops novel acquisition and reconstruction strategies and in close collaboration with clinicians to develop better and more efficient techniques aimed improving the diagnosis of heart disease and cancer. One of the major goals is to be able to derive parameters for the quantification of disease from data acquired within the time constraints of a clinical MRI examination. The idea is to complement the current qualitative-approach of clinical radiology with a quantitative or "parametric" approach. This should not only improve the accuracy in diagnosis but it should also allow radiologists to interpret data faster. One of the major goals is to develop acquisition and reconstructions strategies that can yield quantitative parameters for the characterization of disease.

Degrees
  • PhD: Louisiana State University, 1988

Select Publications

2021

Li, Z., Z. Fu, M. Keerthivasan, A. Bilgin, K. Johnson, J-P. Galons, S. Vedantham, D. R. Martin, and M. I. Altbach, "Rapid high-resolution volumetric T mapping using a highly accelerated stack-of-stars Look Locker technique.", Magn Reson Imaging, vol. 79, pp. 28-37, 2021 Mar 17. PMID: 33722634

2018

Li, Z., A. Bilgin, K. Johnson, J-P. Galons, S. Vedantham, D. R. Martin, and M. I. Altbach, "Rapid High-Resolution T Mapping Using a Highly Accelerated Radial Steady-state Free-precession Technique.", J Magn Reson Imaging, 2018 Aug 24.
Keerthivasan, MB., B. Winegar, JL. Becker, A. Bilgin, M. Altbach, and M. Saranathan, Clinical Utility of a Novel Ultrafast T2-Weighted Sequence for Spine Imaging, 2018.
Ding, J., A. T. Stopeck, Y. Gao, M. T. Marron, B. C. Wertheim, M. I. Altbach, J-P. Galons, D. J. Roe, F. Wang, G. Maskarinec, et al., "Reproducible automated breast density measure with no ionizing radiation using fat-water decomposition MRI.", J Magn Reson Imaging, vol. 48, issue 4, pp. 971-981, 2018 Oct. PMCID: PMC6173993  PMID: 29630755
Keerthivasan, M. B., B. Winegar, J. L. Becker, A. Bilgin, M. I. Altbach, and M. Saranathan, "Clinical Utility of a Novel Ultrafast T2-Weighted Sequence for Spine Imaging.", AJNR Am J Neuroradiol, vol. 39, issue 8, pp. 1568-1575, 2018 08. PMCID: PMC7410539 
Blew, R., T. Lohman, V. Lee, MI. Altbach, JP. Galons, S. Going, J. Bea, and M. Hetherington-Rauth, Validation of pQCT-Derived Thigh Adipose Tissue Sub-Compartments in Young Girls Using a 3T MRI Scanner, 2018.
Bilgin, A., K. Johnson, D. Martin, and M. Altbach, High-resolution 3D T1 mapping of the prostate with an efficient inversion-recovery radial FLASH, 2018.
Mandava, S., M. Keerthivasan, Z. Li, DR. Martin, MI. Altbach, and A. Bilgin, Accelerated MR Parameter Mapping with a Union of Local Subspaces Constraint, 2018.
Altbach, M., K. Johnson, M. Keerthisavan, J. Becker, and A. Bilgin, Rapid Carotid Artery T2 and T1 Mapping Using a Radial TSE and IR-FLASH Approach, 2018.
Keerthivasan, MB., S. Mandava, K. Johnson, R. Avery, R. Janardhanan, DR. Martin, A. Bilgin, and MI. Altbach, A Multi-Band Double-Inversion Radial Fast Spin-Echo Technique for T2 Mapping of the Heart, 2018.

2017

Pandey, A., U. Yoruk, M. Keerthivasan, J-P. Galons, P. Sharma, K. Johnson, D. R. Martin, M. I. Altbach, A. Bilgin, and M. Saranathan, "Multiresolution imaging using golden angle stack-of-stars and compressed sensing for dynamic MR urography.", J Magn Reson Imaging, vol. 46, issue 1, pp. 303-311, 2017 Jul.
Thomson, C. A., H. H. Sherry Chow, B. C. Wertheim, D. J. Roe, A. Stopeck, G. Maskarinec, M. Altbach, P. Chalasani, C. Huang, M. B. Strom, et al., "A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.", Breast Cancer Res Treat, vol. 165, issue 1, pp. 97-107, 2017 Aug. PMCID: PMC5571834  PMID: 28560655
Rosado-Toro, J. A., A. Abidov, M. I. Altbach, I. B. Oliva, J. J. Rodriguez, and R. J. Avery, "Segmentation of the right ventricle in four chamber cine cardiac MR images using polar dynamic programming.", Comput Med Imaging Graph, 2017 Aug 18. PMID: 28886885
Keerthivasan, MB., A. Bilgin, KJ. Johnson, and MI. Altbach, Flexible and Efficient 2D Radial TSE T2 Mapping with Tiered Echo Sharing and with “Pseudo” Golden Angle Ratio Reordering, 2017.

2016

JA, M., C. P, T. CA, R. D, A. M, and et. al Galons J-P, "Phase II study of metformin for reduction of obesity-associated breast cancer risk: a randomized controlled trial protocol", BMC Cancer, 07/2016.
Brand, J. F., L. R. Furenlid, M. I. Altbach, J-P. Galons, A. Bhattacharyya, P. Sharma, T. Bhattacharyya, A. Bilgin, and D. R. Martin, "Task-based optimization of flip angle for fibrosis detection in T1-weighted MRI of liver.", J Med Imaging (Bellingham), vol. 3, issue 3, pp. 035502, 2016 Jul. PMCID: PMC4955011  PMID: 27446971

2015

Berman, B. P., A. Pandey, Z. Li, L. Jeffries, T. P. Trouard, I. Oliva, F. Cortopassi, D. R. Martin, M. I. Altbach, and A. Bilgin, "Volumetric MRI of the lungs during forced expiration.", Magn Reson Med, 2015 Jul 3.

1999

Trouard, T. P., R. J. Theilmann, M. I. Altbach, and A. F. Gmitro, "High-resolution diffusion imaging with DIFRAD-FSE (diffusion-weighted radial acquisition of data with fast spin-echo) MRI.", Magn Reson Med, vol. 42, issue 1, pp. 11-8, 1999 Jul. PMID: 10398944
Raghunand, N., M. I. Altbach, R. van Sluis, B. Baggett, C. W. Taylor, Z. M. Bhujwalla, and R. J. Gillies, "Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy.", Biochem Pharmacol, vol. 57, issue 3, pp. 309-12, 1999 Feb 01.

1997

Trouard, T. P., M. I. Altbach, G. C. Hunter, C. D. Eskelson, and A. F. Gmitro, "MRI and NMR spectroscopy of the lipids of atherosclerotic plaque in rabbits and humans.", Magn Reson Med, vol. 38, issue 1, pp. 19-26, 1997 Jul. PMID: 9211375

1996

Trouard, T. P., Y. Sabharwal, M. I. Altbach, and A. F. Gmitro, "Analysis and comparison of motion-correction techniques in diffusion-weighted imaging.", J Magn Reson Imaging, vol. 6, issue 6, pp. 925-35, 1996 Nov-Dec. PMID: 8956139

1995

Inisan, A. G., S. Meunier, O. Fedelli, M. Altbach, V. Fremont, J. M. Sabatier, A. Thévan, J. M. Bernassau, C. Cambillau, and H. Darbon, "Structure-activity relationship study of a scorpion toxin with high affinity for apamin-sensitive potassium channels by means of the solution structure of analogues.", Int J Pept Protein Res, vol. 45, issue 5, pp. 441-50, 1995 May.

1986

Altbach, M. I., CA. Muedas, RP. Korswagen, and ML. Ziegler, "1H NMR Study of the Reversible cis/trans Isomerization of {(-CH2)( -CO)[h5-C5H5)Fe(CO)]2}", Journal of organometallic chemistry, pp. 306:375, 1986.
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