Arthur F. Gmitro, PhD

Professor, Medical Imaging
Department Head, Biomedical Engineering
Professor, Biomedical Engineering
Professor, Optical Sciences

I have been involved in medical imaging for over 30 years and have done research work in technology development in CT, MRI, and optical imaging. I have applied these technologies in clinical and research applications including neurological imaging, body imaging, and cancer. The focus of my research is on development of new imaging technologies and their application in basic and applied clinical science. A current area of research in my laboratory is in the development of optical biopsy systems for cancer detection. We have pioneered the development of the confocal microendoscope and are actively involved in developing and testing this technology in the area of cancer diagnosis. My laboratory is also working to develop a multi-modality imaging platform utilizing window chambers animal models to enable better preclinical testing of novel cancer diagnostic and therapeutic approaches. We have developed and used the window chamber models to measure pH, angiogenesis, vascular permeability, and molecular expression profiles using optical, MRI, and nuclear imaging modalities.

Degrees
  • PhD: University of Arizona, Optical Sciences, Tucson - 1982
  • MS: University of Arizona, Optical Sciences, Tucson - 1979
Honors and Awards
  • Fellow American Institute for Medical and Biological Engineering 2011
  • Fenton Maynard Endowed Chair in Cancer Imaging 2009
  • Francois Erbsmann Prize, IPMI, 1989
  • Rudolph Kingslake Award, SPIE, 1984
  • Regents Scholarship, University of Arizona, 1976

Select Publications

2021

Larson, M. C., A. F. Gmitro, U. Utzinger, A. R. Rouse, G. J. Woodhead, Q. Carlson, C. T. Hennemeyer, and J. K. Barton, "Using FDA-approved drugs as off-label fluorescent dyes for optical biopsies: from in silico design toproof-of-concept.", Methods Appl Fluoresc, vol. 9, issue 3, 2021 Jun 04.

2016

Risi, M. D., A. R. Rouse, S. K. Chambers, K. D. Hatch, W. Zheng, and A. F. Gmitro, "Pilot Clinical Evaluation of a Confocal Microlaparoscope for Ovarian Cancer Detection.", Int J Gynecol Cancer, vol. 26, issue 2, pp. 248-54, 2016 Feb. PMCID: PMC4728032  PMID: 26745695

2014

Wu, T-Y., A. R. Rouse, S. K. Chambers, K. D. Hatch, and A. F. Gmitro, "Confocal microlaparoscope for imaging the fallopian tube.", J Biomed Opt, vol. 19, issue 11, pp. 116010, 2014 Nov. PMCID: PMC4409019  PMID: 25411899
Risi, MD., H. Makhlouf, AR. Rouse, AA. Tanbakuchi, and AF. Gmitro, "Design and Performance of a Multi-Point Scan Confocal Microendoscope", Photonics, vol. 1, issue 4, 2014.

2011

Makhlouf, H., A. R. Rouse, and A. F. Gmitro, "Dual modality fluorescence confocal and spectral-domain optical coherence tomography microendoscope.", Biomed Opt Express, vol. 2, issue 3, pp. 634-44, 2011. PMCID: PMC3047368 

2010

Tanbakuchi, A. A., J. A. Udovich, A. R. Rouse, K. D. Hatch, and A. F. Gmitro, "In vivo imaging of ovarian tissue using a novel confocal microlaparoscope.", Am J Obstet Gynecol, vol. 202, issue 1, pp. 90.e1-9, 2010 Jan. PMCID: PMC2811223  PMID: 19800605

2008

Taljanovic, M. S., A. R. Graham, J. B. Benjamin, A. F. Gmitro, E. A. Krupinski, S. A. Schwartz, T. B. Hunter, and D. L. Resnick, "Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology.", Skeletal Radiol, vol. 37, issue 5, pp. 423-31, 2008 May.

1997

Trouard, T. P., M. I. Altbach, G. C. Hunter, C. D. Eskelson, and A. F. Gmitro, "MRI and NMR spectroscopy of the lipids of atherosclerotic plaque in rabbits and humans.", Magn Reson Med, vol. 38, issue 1, pp. 19-26, 1997 Jul. PMID: 9211375

1996

Trouard, T. P., Y. Sabharwal, M. I. Altbach, and A. F. Gmitro, "Analysis and comparison of motion-correction techniques in diffusion-weighted imaging.", J Magn Reson Imaging, vol. 6, issue 6, pp. 925-35, 1996 Nov-Dec. PMID: 8956139