Theodore Trouard, PhD

Professor, Biomedical Engineering and Medical Imaging
Assistant Director, BIO5 Institute

Theodore P. Trouard, PhD is a leader in development and biomedical application of magnetic resonance imaging, or MRI, technologies. His lab has developed techniques that allow very clear MRI images of stroke that aid in treatment. Dr. Trouard’s imaging techniques also are being used to better diagnose and treat cancer, Alzheimer's disease and Niemann-Pick type C disease. His work also includes using mathematical models that simulate water movement within living tissue to deepen our understanding of what MRI tells us about the body.

Dr. Trouard leads an MRI group at the University of Arizona and collaborates with radiologists, pediatricians, neuroscientists, oncologists, geneticists and engineers at University’s Colleges of Engineering, Medicine and Sciences. He also works with scientists throughout the world who are seeking to improve MRI applications for early detection and monitoring of neurological disease and Cancer as well as understand the processes of normal aging of the brain.

Select Publications

In Press

Stephen, RM., AK. Jha, D. Roe, T. Trouard, and MA. Kupinskil, "Diffusion MRI with Semi-Automated Segmentation Can Serve as a Restricted Predictive Biomarker of the Therapeutic Response of Liver Metastasis", Magnetic Resonance Imaging, In Press.

2020

Valdez, M. A., E. Fernandez, T. Matsunaga, R. P. Erickson, and T. P. Trouard, "Distribution and Diffusion of Macromolecule Delivery to the Brain via Focused Ultrasound using Magnetic Resonance and Multispectral Fluorescence Imaging.", Ultrasound Med Biol, vol. 46, issue 1, pp. 122-136, 2020 Jan. PMCID: PMC6937597  PMID: 31585767

2017

Totenhagen, J. W., A. Bernstein, E. S. Yoshimaru, R. P. Erickson, and T. P. Trouard, "Quantitative magnetic resonance imaging of brain atrophy in a mouse model of Niemann-Pick type C disease.", PLoS One, vol. 12, issue 5, pp. e0178179, 2017. PMCID: PMC5443551 

2011

Harkins, K. D., J-P. Galons, J. L. Divijak, and T. P. Trouard, "Changes in intracellular water diffusion and energetic metabolism in response to ischemia in perfused C6 rat glioma cells.", Magn Reson Med, vol. 66, issue 3, pp. 859-67, 2011 Sep. PMCID: PMC3621130  PMID: 21446036

2009

Harkins, K. D., J-P. Galons, T. W. Secomb, and T. P. Trouard, "Assessment of the effects of cellular tissue properties on ADC measurements by numerical simulation of water diffusion.", Magn Reson Med, vol. 62, issue 6, pp. 1414-22, 2009 Dec. PMCID: PMC2855231  PMID: 19785014

2008

Trouard, T. P., K. D. Harkins, J. L. Divijak, R. J. Gillies, and J-P. Galons, "Ischemia-induced changes of intracellular water diffusion in rat glioma cell cultures.", Magn Reson Med, vol. 60, issue 2, pp. 258-64, 2008 Aug. PMCID: PMC10029360  PMID: 18666112

2003

Guo, J., R. Erickson, T. Trouard, J-P. Galons, and R. Gillies, "Magnetization transfer contrast imaging in Niemann pick type C mouse liver.", J Magn Reson Imaging, vol. 18, issue 3, pp. 321-7, 2003 Sep. PMID: 12938127

1997

Trouard, T. P., M. I. Altbach, G. C. Hunter, C. D. Eskelson, and A. F. Gmitro, "MRI and NMR spectroscopy of the lipids of atherosclerotic plaque in rabbits and humans.", Magn Reson Med, vol. 38, issue 1, pp. 19-26, 1997 Jul. PMID: 9211375

1996

Trouard, T. P., Y. Sabharwal, M. I. Altbach, and A. F. Gmitro, "Analysis and comparison of motion-correction techniques in diffusion-weighted imaging.", J Magn Reson Imaging, vol. 6, issue 6, pp. 925-35, 1996 Nov-Dec. PMID: 8956139