Andrew Karellas, PhD, DABR, FAAPM, FACR

Professor Emeritus of Medical Imaging

Andrew Karellas, PhD, DABR, FAAPM, FACR is Professor Emeritus of Medical Imaging at the University of Arizona, College of Medicine-Tucson. Dr. Karellas joined the Department of Medical Imaging as the Director of Biomedical Imaging Innovation and Clinical Translation in Next-Gen CT and Vice Chair of Faculty Development. Prior to arriving in Arizona, Dr. Karellas was a tenured professor at the University of Massachusetts Medical School.

Dr. Karellas received his PhD from UCLA in Medical Physics. He has been Professor of Radiology, Hematology and Oncology at the Winship Cancer Institute of Emory University, Professor of Biomedical Engineering at the Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and the Acting Vice-Chair for Research at the Department of Radiology, Emory University School of Medicine.  Dr. Karellas is certified in Diagnostic Radiological Physics by the American Board of Radiology.

Dr. Karellas has received numerous honors and awards. He is a Fellow of the American College of Radiology (2012), a Fellow of the American Association of Physicists in Medicine (2001), and a member of Sigma Xi (1984). He received a Dedicated Service Recognition Award as a Deputy Editor for Medical Physics, a Lifetime Achievement Award from the Upstate New York Association of Physicists in Medicine, and a Lifetime Service Award from the American Board of Radiology. He was also recognized as an “SPIE Senior Member,” a distinction awarded for his significant contributions, active involvement, and service to the general optics and photonics community and his contributions to relevant technologies.

Dr. Karellas holds patents for Quantitative Radiographic Imaging Systems and Digital and Tomosynthesis Imaging and is the recipient of several research support grants from NIH.

Degrees
  • PhD: UCLA, Medical Physics
Honors and Awards
  • Fellow, American College of Radiology - 2012
  • Fellow, American Association of Physicists in Medicine - 2001
  • Dedicated Service Recognition Award as Deputy Editor for Medical Physics
  • Lifetime Achievement Award, Update New York Associate of Physicists in Medicine
  • Lifetime Achievement Award, American Board of Radiology
  • SPIE Senior Member
  • Member of Xigma Xi - 1984

Select Publications

2022

Tseng, H. Wu, A. Karellas, and S. Vedantham, "Cone-beam breast CT using an offset detector: effect of detector offset and image reconstruction algorithm.", Phys Med Biol, vol. 67, issue 8, 2022 Apr 07. PMID: 35316793
Karellas, A., A. RJ, C. MF, E. J, J. CE, S. M, S. P, and V. S, Continuous Professional Improvement (CPI) Physics in Imaging Special Edition Module: American College of Radiology (ACR) , 2022.
Vedantham, S., and A. Karellas, "Breast Cancer Screening: Opportunities and Challenges with Fully 3D Tomographic X-Ray Imaging.", Bridge (Wash D C), vol. 52, issue 1, pp. 33-42, 2022 Spring. PMCID: PMC9012464 

2021

Tseng, H., A. Karellas, and S. Vedantham, "Radiation dosimetry of a clinical prototype dedicated cone‐beam breast CT system with offset detector", Medical Physics, 01/2021.

2020

Karellas, A., "Challenges in Dosimetry and Radiation Dose Trends.", Radiology, vol. 294, issue 2, pp. 360-361, 2020 Feb. PMCID: PMC6996600 
Fu, Z., H. Wu Tseng, S. Vedantham, A. Karellas, and A. Bilgin, "A residual dense network assisted sparse view reconstruction for breast computed tomography", Scientific Reports, vol. 10; 21111, 12/2020.
Tseng, H. Wu, A. Karellas, and S. Vedantham, "Sparse-view, short-scan, dedicated cone-beam breast computed tomography: image quality assessment", Biomedical Physics & Engineering Express , vol. 6, issue 6, 09, 2020.
Tseng, H. W., A. Karellas, and S. Vedantham, "Sparse-view, short-scan, dedicated cone-beam breast computed tomography: Image quality assessment.", Biomedical Physics & Engineering Express, vol. 5, 09/ 2020.
Vedantham, S., H. Wu Tseng, S. Konate, L. Shi, and A. Karellas, "Dedicated cone-beam breast CT using laterally-shifted detector geometry: Quantitative analysis of feasibility for clinical translation", Journal of X-Ray Science and Technology,, 04/2020.
Vedantham, S., H-W. Tseng, S. Konate, L. Shi, and A. Karellas, "Dedicated cone-beam breast CT using laterally-shifted detector geometry: Quantitative analysis of feasibility for clinical translation.", J Xray Sci Technol, vol. 28, issue 3, pp. 405-426, 2020. PMCID: PMC7347391  PMID: 32333575
Tseng, H. Wu, S. Vedantham, and A. Karellas, "Cone-beam breast computed tomography using ultra-fast image reconstruction with constrained, total-variation minimization for suppression of artifacts", Physica Medica, vol. 73, 05/2020.

2019

Deng, L., S. Yasar, M. Foiez Ahmed, S. Jayarathna, P. Feng, B. Wei, S. Vedantham, A. Karellas, and S. Hyun Cho, "Investigation of transmission computed tomography (CT) image quality and x-ray dose achievable from an experimental dual-mode benchtop x-ray fluorescence CT and transmission CT system.", J Xray Sci Technol, vol. 27, issue 3, pp. 431-442, 2019. PMCID: PMC7027361  PMID: 30909268
Tseng, H. W., S. Vedantham, S. H. Cho, and A. Karellas, "Joint optimization of collimator and reconstruction parameters in x-ray fluorescence computed tomography using analytical point spread function and model observer.", IEEE Trans Biomed Eng, 2019 Dec 30. PMID: 31899411

2018

O'Connell, A. M., A. Karellas, S. Vedantham, and D. T. Kawakyu-O'Connor, "Newer Technologies in Breast Cancer Imaging: Dedicated Cone-Beam Breast Computed Tomography.", Semin Ultrasound CT MR, vol. 39, issue 1, pp. 106-113, 2018 Feb. PMCID: PMC5957539  PMID: 29317032
Vedantham, S., and A. Karellas, "Emerging Breast Imaging Technologies on the Horizon.", Semin Ultrasound CT MR, vol. 39, issue 1, pp. 114-121, 2018 Feb. PMCID: PMC5773258  PMID: 29317033
Shi, L., S. Vedantham, A. Karellas, and L. Zhu, "The role of off-focus radiation in scatter correction for dedicated cone beam breast CT.", Med Phys, vol. 45, issue 1, pp. 191-201, 2018 Jan. PMCID: PMC5985236  PMID: 29159941

2017

Shi, L., S. Vedantham, A. Karellas, and L. Zhu, "X-ray scatter correction for dedicated cone beam breast CT using a forward-projection model.", Med Phys, vol. 44, issue 6, pp. 2312-2320, 2017 Jun.
Shrestha, S., S. Vedantham, and A. Karellas, "Towards standardization of x-ray beam filters in digital mammography and digital breast tomosynthesis: Monte Carlo simulations and analytical modelling.", Phys Med Biol, vol. 62, issue 5, pp. 1969-1993, 2017 Mar 07. PMCID: PMC5384796  PMID: 28075335