Speaker: Hugh McGregor, MD
Title: Translational Research in Interventional Radiology: New Applications for Percutaneous Ablation, Radiogenomics, and Opportunities for Advanced MR
The Department of Medical Imaging is pleased to have Hugh McGregor, MD, presenting at our Grand Rounds on Tuesday, October 31st, in COM, Room 2117, at 12:00 pm.
Dr. McGrefor is a Fellow in Interventional Radiology at the University of California, San Francisco, in the University of California, San Francisco (UCSF) Medical Center.
Abstract: Radiology is a dynamic field with a wide variety of opportunities for translational research. Two areas of particular interest in Interventional Radiology are percutaneous ablation of tissue and endovascular repair of dialysis arteriovenous fistulas (AVFs). Gallbladder disease is common and high-risk patients may be unable to tolerate surgical cholecystectomy. Minimally invasive percutaneous procedures offer high-risk patients therapeutic alternatives. Gallbladder cryoablation is a percutaneous option that can be performed under CT guidance. This talk will discuss pre-clinical studies in gallbladder cryoablation and future directions. Dialysis AVFs have high failure rates and frequently require percutaneous interventions to maintain patency. While angioplasty and stenting have been moderately successful, the lack of understanding of the molecular mechanisms underlying AVF failure have limited the application of tailored treatment options and pharmacologic therapies. This talk will discuss a novel technique for endothelial cell biopsy during endovascular repair of fistulas and determining gene expression profiles that lead to failure. Opportunities to enhance both these techniques with MR imaging will also be discussed. p>
College of Medicine, Room 2117